Category Name Pain Management — NSAID + Analgesic + Muscle Relaxant Combination
Common Indications Aclopass TH4 Tablet is used to relieve pain and discomfort associated with musculoskeletal conditions, including:
- Acute and chronic muscle pain and spasms
- Back pain and lower back stiffness
- Neck pain and cervical spondylosis
- Sports injuries and strains
- Post-operative or post-traumatic muscular pain
- Inflammatory conditions causing joint and muscle discomfort
Common Dosing
- Standard Adult Dose: One tablet twice daily, or as prescribed by your doctor
- With Food: Always take with or after food to reduce the risk of stomach upset
- Duration: Short-term use only, as directed by your physician. Do not exceed the recommended dose or duration
- Elderly Patients: Use with extra caution; a lower dose or closer monitoring may be required
Always follow your doctor's prescribed dose and duration.
Common Side Effects Most side effects are mild and tend to improve as your body adjusts. These may include:
- Nausea
- Vomiting
- Heartburn
- Stomach pain or discomfort
- Diarrhea
- Loss of appetite
- Dryness in mouth
Consult your doctor promptly if side effects are severe, persistent, or if you notice any signs of stomach bleeding such as dark stools or vomiting blood.
Common Interactions Inform your doctor or pharmacist about all medications, supplements, and herbal products you are currently taking. Notable interactions include:
- Anticoagulants / Antiplatelet drugs (e.g., Warfarin, Aspirin, Clopidogrel) — Aceclofenac may significantly increase the risk of gastrointestinal bleeding
- Other NSAIDs or Corticosteroids (e.g., Ibuprofen, Prednisolone) — Concurrent use increases the risk of stomach ulcers and gastric irritation
- Enzyme-inducing drugs (e.g., Phenytoin, Carbamazepine, Rifampicin) — May interact with Paracetamol and increase the risk of liver toxicity
- CNS Depressants (e.g., sleeping pills, sedatives, anti-anxiety medications, opioids) — Thiocolchicoside may enhance sedation and drowsiness when combined with these agents
Special Instructions
| Condition | Guidance |
|---|---|
| 🤰 Pregnancy | This medication is highly unsafe during pregnancy. It may cause serious harm to the unborn baby, including birth defects and risk of pregnancy loss. Do not use during pregnancy under any circumstances without explicit medical supervision. |
| 🤱 Breastfeeding | May be unsafe during breastfeeding. The components may pass into breast milk and affect the nursing infant. Consult your doctor before use. |
| 🍺 Alcohol | Do not consume alcohol while taking this medicine. Alcohol significantly increases the risk of liver damage and gastrointestinal bleeding when combined with this combination tablet. |
| 🚗 Driving | This medicine may cause drowsiness, dizziness, or blurred vision. Do not drive, operate heavy machinery, or perform tasks requiring high mental alertness until you know how this medicine affects you. |
| 🫀 Liver Disease | Use with caution in patients with liver impairment. Paracetamol at standard doses is generally tolerated, but the risk of liver toxicity is higher in those with pre-existing liver conditions. Regular liver function monitoring is advised. |
| 🫘 Kidney Disease | Use with caution in patients with kidney disease. Aceclofenac may reduce kidney blood flow and impair kidney function. Avoid use in severe renal impairment unless specifically directed by a physician. |
Mechanism of Action Aclopass TH4 is a triple-combination tablet that works through three complementary pathways:
- Aceclofenac (NSAID): Blocks the COX enzyme pathway, reducing the production of prostaglandins — the chemical messengers responsible for pain, inflammation, and swelling
- Paracetamol (Analgesic/Antipyretic): Acts centrally in the brain to raise the pain threshold and reduce fever by inhibiting pain signal transmission
- Thiocolchicoside (Muscle Relaxant): Acts on receptors in the brain and spinal cord (GABA and glycine receptors) to reduce muscle stiffness, spasm, and rigidity, thereby improving muscle movement and flexibility
Together, these three components provide comprehensive relief from pain, inflammation, and muscle spasm.
Instructions to Take
- Take this tablet with or after food to minimize stomach discomfort
- Swallow the tablet whole with a full glass of water — do not crush or chew
- Take it at regular intervals as prescribed; do not self-adjust the dose
- Do not take more than the recommended dose — excess Paracetamol can cause serious liver damage
- Avoid long-term use without medical supervision
- If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose — do not double up
- Store in a cool, dry place away from direct sunlight and out of reach of children
This information is intended for general reference purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, changing, or stopping any medication.
