Rabeprazole Sodium 20mg, Domperidone 30mg.
Rs.83.16
Product Details
Product Details
Product Details
Get all-day relief from severe heartburn, acid reflux, and bloating with RABVENTIS-DSR. A powerful dual-action formula for complete digestive comfort.
Category Name Gastroenterology — Proton Pump Inhibitor (PPI) + Prokinetic Agent Combination
Common Indications
- Gastroesophageal Reflux Disease (GERD)
- Functional dyspepsia with bloating, nausea, and regurgitation
- Gastric and duodenal ulcers
- H. pylori eradication (as part of triple therapy)
- Erosive esophagitis
- Delayed gastric emptying (gastroparesis)
- NSAID-associated gastric symptoms
Common Dosing
- Standard Adult Dose: One capsule/tablet once daily, 30–60 minutes before breakfast
- Duration: 4–8 weeks or as prescribed
- Sustained Release (DSR): Do not crush or chew
Always follow your doctor's prescribed dose and duration.
Common Side Effects
- Dryness in mouth
- Headache and dizziness
- Nausea
- Diarrhoea or constipation
- Flatulence
Seek immediate attention for:
- Palpitations or irregular heartbeat (QT prolongation — Domperidone)
- Severe allergic reactions
Common Interactions
- QT-prolonging drugs (e.g., Erythromycin, Ketoconazole, Antiarrhythmics) — Increased cardiac arrhythmia risk with Domperidone
- Warfarin, Diazepam — Rabeprazole may increase their plasma levels
- Ketoconazole, Itraconazole, Atazanavir — Reduced absorption due to higher gastric pH
- Methotrexate (high dose) — Risk of increased toxicity with PPI co-administration
Special Instructions
| Condition | Guidance |
|---|---|
| 🤰 Pregnancy | Not recommended. Consult your doctor. |
| 🤱 Breastfeeding | Unsafe. Both components may pass into breast milk. |
| 🍺 Alcohol | Avoid. Worsens reflux and increases gastric irritation. |
| 🚗 Driving | May cause dizziness. Exercise caution. |
| 🫀 Liver Disease | Use with caution in severe hepatic impairment. |
| 🫘 Kidney Disease | Generally safe. Monitor in severe renal impairment. |
Mechanism of Action
- Rabeprazole (PPI): Irreversibly inhibits the gastric H+/K+ ATPase proton pump, potently suppressing gastric acid secretion. Rabeprazole has a faster onset of action compared to many other PPIs
- Domperidone (Prokinetic): Blocks peripheral dopamine D2 receptors, accelerating gastric emptying and improving upper GI motility — reducing bloating, nausea, and regurgitation
Together they address both excess acid secretion and impaired gastric motility.
Instructions to Take
- Take 30–60 minutes before breakfast
- Swallow whole — do not crush or chew (DSR formulation)
- Complete the full prescribed course
- Take at the same time each day
- Store in a cool, dry place away from sunlight
This information is intended for general reference purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, changing, or stopping any medication.
