Category Name Supplements / Vascular Protective & Capillary Stabilising Agent
Common Indications YUVICAL-D is indicated for the management of venous and microvascular disorders requiring capillary stabilisation and improved blood circulation. It is commonly prescribed for:
- Haemorrhoids (piles) with associated pain, swelling, irritation, and itching
- Varicose veins and chronic venous insufficiency
- Diabetic retinopathy requiring microvascular protective therapy
- Chronic venous oedema and leg heaviness associated with poor venous circulation
- Microangiopathy (damage to small blood vessels) associated with diabetes
- Capillary fragility and increased vascular permeability leading to bruising or bleeding tendency
- Post-operative management of haemorrhoids and venous disorders to promote healing and reduce inflammation
Common Dosings One capsule (500 mg) orally, two to three times daily after food — or as directed by your physician. The dose and duration of therapy should be determined by the treating physician based on the condition being treated, severity of symptoms, and clinical response. For chronic venous conditions, a prolonged course of therapy may be required under medical supervision. Do not self-adjust the dose or discontinue therapy without consulting your doctor.
Common Side Effects The following side effects may occur during the course of treatment. Consult your doctor if any of these persist or worsen:
- Skin rash or urticaria
- Fever or chills
- Nausea or upset stomach
- Vomiting
- Abdominal discomfort with higher doses
- Joint pain or arthralgia with prolonged use — inform your doctor if experienced
- Serious allergic reactions such as facial swelling, difficulty breathing, or severe skin reactions — seek immediate medical attention if severe
Common Interactions Inform your doctor about all medications, supplements, and herbal products you are currently taking. Notable interactions include:
- Antiplatelet Drugs (Aspirin, Clopidogrel): Concurrent use should be exercised with caution as Calcium Dobesilate may enhance antiplatelet activity, potentially increasing the risk of bleeding — use only under medical supervision with regular monitoring
- Anticoagulants (Warfarin, Heparin): Combined use may enhance anticoagulant effects and increase bleeding risk — regular INR monitoring and close clinical observation are recommended
- Drugs Affecting Vascular Circulation or Microcirculation: Concomitant use with other vasoactive or microcirculatory agents should be monitored by a physician to avoid additive or unpredictable vascular effects
- Antidiabetic Medications: In diabetic patients using Calcium Dobesilate for diabetic microangiopathy, blood glucose levels should be monitored regularly as part of comprehensive diabetes management
Special Instructions
| Condition | Guidance |
|---|---|
| Pregnancy | Adequate safety data during pregnancy is not currently available. Use only if clearly indicated and under strict medical supervision after careful benefit-risk evaluation by the treating physician. |
| Breastfeeding | Adequate safety data during breastfeeding is not currently available. Consult your doctor before use during lactation. |
| Alcohol | Unsafe to consume alcohol during therapy. Alcohol may worsen venous congestion, increase vascular fragility, and counteract the therapeutic benefits of this medicine — strictly avoid alcohol during the course of treatment. |
| Driving & Machinery | Does not usually impair alertness or driving ability. Safe to drive under normal conditions of use unless you experience unusual dizziness or discomfort. |
| Liver Disease | Limited clinical data available in patients with hepatic impairment. Use with caution and under close medical supervision — consult your physician for individualised guidance. |
| Kidney Disease | Limited clinical data available in patients with renal impairment. Use with caution and under close medical supervision — consult your physician for individualised dosing guidance. |
Mechanism of Action YUVICAL-D contains Calcium Dobesilate, a synthetic vasoprotective and capillary stabilising agent that exerts its therapeutic effect through multiple complementary mechanisms targeting the microvascular system:
Calcium Dobesilate works primarily by acting on the walls of small blood vessels (capillaries and venules), reducing their abnormal permeability and fragility. By strengthening the structural integrity of capillary walls, it prevents excessive fluid leakage from blood vessels into surrounding tissues, thereby reducing oedema, swelling, and tissue congestion.
In addition, Calcium Dobesilate improves microcirculatory blood flow by reducing blood viscosity (thickness), inhibiting platelet aggregation, and decreasing the adhesion of red blood cells to vessel walls. This results in improved blood fluidity and more efficient circulation through the microvasculature.
Its antioxidant properties further contribute to its therapeutic effect by neutralising free radicals and reducing oxidative stress at the vascular endothelium, promoting tissue healing and reducing inflammation in conditions such as haemorrhoids and venous insufficiency.
Together, these actions — capillary wall stabilisation, reduced vascular permeability, improved blood rheology, and antioxidant protection — make Calcium Dobesilate an effective and well-tolerated agent for the comprehensive management of venous and microvascular disorders.
Instructions to Take
- Take this capsule exactly as prescribed by your doctor
- Always take after food to minimise the risk of stomach discomfort and nausea
- Swallow the capsule whole with a full glass of water — do not crush, open, or chew
- Take at regular intervals as prescribed to maintain consistent therapeutic drug levels
- For chronic venous conditions, complete the full prescribed course even if symptoms improve — do not discontinue therapy prematurely without consulting your doctor
- Maintain adequate hydration during the course of therapy to support vascular circulation and overall recovery
- Do not self-medicate, adjust the dose, or add other vascular or anticoagulant medications without medical advice
- If a dose is missed, take it as soon as you remember — however, skip the missed dose if it is almost time for the next scheduled dose. Do not double the dose to make up for a missed one
- Strictly avoid alcohol throughout the course of treatment
- Keep out of reach of children
- Store in a cool, dry place away from direct sunlight and moisture
Disclaimer: This information is intended for general reference purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, changing, or stopping any medication.
