Amoxycillin I.P. 500 mg + Clavulanate Potassium I.P. 125 mg (Foil packing)
Rs.150.54 Rs.195.50
Product Details
Product Details
Product Details
Treat severe infections with YUVICLAV 625. Premium Amoxycillin & Clavulanate Potassium antibiotic in protective Foil Packing for maximum stability.
Category Name Anti-Infectives — Broad-Spectrum Antibiotic + Beta-Lactamase Inhibitor Combination
Common Indications
- Upper and lower respiratory tract infections — sinusitis, tonsillitis, bronchitis, pneumonia
- Urinary tract infections (UTIs)
- Skin and soft tissue infections
- Dental infections and oral abscesses
- Ear infections (otitis media)
- Gynaecological infections
- Infections caused by beta-lactamase-producing resistant organisms
Common Dosing
- Standard Adult Dose: One tablet (625 mg) three times daily, with or after food, every 8 hours
- Duration: 5–14 days depending on infection type and severity
- Complete the Full Course without skipping doses
Always follow your doctor's prescribed dose and duration.
Common Side Effects
- Nausea, vomiting, and diarrhoea
- Abdominal discomfort and bloating
- Skin rash or urticaria
- Headache
- Elevated liver enzymes (with prolonged use)
Seek immediate attention for:
- Anaphylaxis or severe allergic reaction
- Severe persistent diarrhoea (C. difficile colitis)
- Jaundice, dark urine, or signs of liver toxicity
Common Interactions
- Warfarin — May enhance anticoagulant effect; monitor INR
- Methotrexate — Amoxycillin may reduce its renal clearance, increasing toxicity risk
- Oral contraceptives — May reduce contraceptive reliability
- Probenecid — Increases Amoxycillin plasma levels
- Allopurinol — Increases risk of skin rash
Special Instructions
| Condition | Guidance |
|---|---|
| 🤰 Pregnancy | Generally considered safe under medical supervision. Consult your doctor before use. |
| 🤱 Breastfeeding | Use with caution. Small amounts pass into breast milk. Monitor infant for diarrhoea or rash. |
| 🍺 Alcohol | Avoid alcohol during antibiotic course to support recovery. |
| 🚗 Driving | May cause dizziness in some individuals. Exercise caution. |
| 🫀 Liver Disease | Use with caution and monitor liver function with prolonged use. |
| 🫘 Kidney Disease | Dose adjustment required in significant renal impairment. |
Mechanism of Action
- Amoxycillin (Aminopenicillin): Inhibits bacterial cell wall synthesis by binding to PBPs, disrupting peptidoglycan cross-linking and causing osmotic lysis of susceptible bacteria
- Clavulanate Potassium (Beta-Lactamase Inhibitor): Irreversibly inhibits beta-lactamase enzymes produced by resistant bacteria, protecting Amoxycillin from degradation and restoring its activity against resistant strains including Staphylococci and H. influenzae
Instructions to Take
- Take with or immediately after food to reduce nausea and improve absorption
- Swallow whole with a full glass of water
- Take at evenly spaced intervals (every 8 hours) for consistent antibiotic levels
- Complete the full prescribed course without interruption
- If you miss a dose, take as soon as remembered — do not double up
- Store in a cool, dry place away from moisture
This information is intended for general reference purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, changing, or stopping any medication.
